Kallikreins (KLKs) belong to the serine protease family of proteolytic enzymes. Kallikrein-8 (KLK8), also called neuropsin precursor, ovasin or serine protease 19, is a 260 amino acid secreted protein involved in hippocampal plasticity. Two isoforms exist for this protein. Isoform 1 is the primary form of KLK8 found predomitly in the pancreas. Isoform 2 contains an additional 46 amino acids after amino acid 23 and is predomitly expressed in adult brain and hippocampus. Isoform 2 is not common to the mouse homolog or other primate homologs. In humans, the T to A mutation (c.71-127T>A) leads ...
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100 µL
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100 µL
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20 µL
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100 µL
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100 µg
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100 µL
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